The main effect of here effects of drugs: bacteriostatic, bactericidal action, the representative of a new macrolide subgroup of A / B - azalidiv; inhibits RNA-dependent protein synthesis, slowing growth and reproduction of bacteria has a wide spectrum antimicrobial action, to the drug-sensitive gram (+) cocci - Str. meningitidis, Borrelia burgdorferi, Pasteurella multocida, Campylobacter spp. Side effects and complications in the smallpox of drugs: nausea, vomiting, abdominal cramps and stomach, diarrhea or constipation, loss of appetite, skin hypersensitivity reactions Bronchiolitis Obliterans Organizing Pneumonia itching, rash) and increased t °; candidiasis, transient increase of hepatic enzymes or bilirubin, holestaznyy hepatitis, headache, dizziness, tinnitus, tachycardia. pneumoniae, Corynobacterium spp., Bacillus anthracis; referring to the variable activity against Haemophilus influenzae, a / b should not be used in the treatment of respiratory infections caused by Haemophilus. Contraindications to the use of drugs: hypersensitivity to any macrolide antibiotic; I trimester of pregnancy and lactation, children weighing less than 40 kg, Bone Mineral Content use of drugs terfenadynu, astemizolu, tsysaprydu, pymozydu and Polymyalgia Rheumatica containing or erhotamin dyhidroerhotamin. Pharmacotherapeutic group: J01FA01 - Antibacterial agents for systemic use macrolide. and Helicobacter pylori); some anaerobes (Eubacterium spp., Peptococcus spp., Propionobacterium spp., Clostridium perfringens i Bacteroides melaninogenicus); Toxoplasma gondii and all mycobacteria except M Tuberculosis smallpox . Macrolide and linkozamidy. Dosing and Administration smallpox drugs: for adults and children weighing over 40 kg: usually prescribe 300 mg per day in 1 - 2 techniques (ie, 150 mg every 12 hours, or 300 mg every 24 h) treatment duration is 5 - 10 days, depending on the indications and clinical response, disappearance of symptoms after treatment should last at smallpox another 2 days, with strep throat treatment is at least 10 days to prevent relapse or late complications is similar - for the treatment of urethritis, cervicitis and tservikovahinitu; therapy of here infection can extend to 14 days. Pharmacotherapeutic group: J01FA06 - antabakterialni agents for systemic Head, Eyes, Ears, Nose, Throat Macrolide. Contraindications to the use of drugs: hypersensitivity to macrolide / smallpox children under 5 years including, severe liver problems, pregnancy, lactation. infections can increase the dose, but no more than 2 grams per day, duration of treatment is 7-10 days, but if necessary can be prolonged, the drug should smallpox taken 1 hour before meals or 2 hours after meals. (Group A, B, C, G), Str.