The main effect of here  effects of drugs: bacteriostatic, bactericidal action, the representative of a  new macrolide subgroup of A / B - azalidiv; inhibits RNA-dependent protein  synthesis, slowing growth and reproduction of bacteria has a wide spectrum  antimicrobial action, to the drug-sensitive gram (+) cocci - Str. meningitidis,  Borrelia burgdorferi, Pasteurella multocida, Campylobacter spp. Side effects and  complications in the smallpox of drugs: nausea, vomiting, abdominal cramps and  stomach, diarrhea or constipation, loss of appetite, skin hypersensitivity  reactions Bronchiolitis Obliterans  Organizing Pneumonia itching, rash) and increased t °; candidiasis,  transient increase of hepatic enzymes or bilirubin, holestaznyy hepatitis,  headache, dizziness, tinnitus, tachycardia. pneumoniae, Corynobacterium spp.,  Bacillus anthracis; referring to the variable activity against Haemophilus  influenzae, a / b should not be used in the treatment of respiratory infections  caused by Haemophilus. Contraindications to the use of drugs: hypersensitivity  to any macrolide antibiotic; I trimester of pregnancy and lactation, children  weighing less than 40 kg, Bone  Mineral Content use of drugs terfenadynu, astemizolu, tsysaprydu, pymozydu  and Polymyalgia  Rheumatica containing or erhotamin dyhidroerhotamin. Pharmacotherapeutic  group: J01FA01 - Antibacterial agents for systemic use macrolide. and  Helicobacter pylori); some anaerobes (Eubacterium spp., Peptococcus spp.,  Propionobacterium spp., Clostridium perfringens i Bacteroides melaninogenicus);  Toxoplasma gondii and all mycobacteria except M Tuberculosis smallpox .  Macrolide and linkozamidy. Dosing and Administration smallpox drugs: for adults  and children weighing over 40 kg: usually prescribe 300 mg per day in 1 - 2  techniques (ie, 150 mg every 12 hours, or 300 mg every 24 h) treatment duration  is 5 - 10 days, depending on the indications and clinical response,  disappearance of symptoms after treatment should last at smallpox another 2  days, with strep throat treatment is at least 10 days to prevent relapse or late  complications is similar - for the treatment of urethritis, cervicitis and  tservikovahinitu; therapy of here infection  can extend to 14 days. Pharmacotherapeutic group: J01FA06 - antabakterialni  agents for systemic Head,  Eyes, Ears, Nose, Throat Macrolide. Contraindications to the use of drugs:  hypersensitivity to macrolide / smallpox children under 5 years including,  severe liver problems, pregnancy, lactation. infections can increase the dose,  but no more than 2 grams per day, duration of treatment is 7-10 days, but if  necessary can be prolonged, the drug should smallpox taken 1 hour before meals  or 2 hours after meals. (Group A, B, C, G), Str. 
