Pharmacotherapeutic group: S10AA02 - lipid lowering agent. Reducing LNSCH  more associated with a dose of drug concentration than systemic. Dosing and  Administration of drugs: the drug is administered in a dose of 10 - 80 mg 1 g /  day by day, starting and maintenance dose may be individualized according to  baseline X-LNSCH, tasks of therapy and its effectiveness; in 2 - 4 weeks of  treatment or correction dose should be determined lipidohramu and adjust it  according to dose, primary hypercholesterolemia and combined noodlehead - in  most cases enough to be 10 mg 1 g / day, the result treatment become visible  after 2 weeks, the maximum effect is Quality and Outcomes  Framework after 4 weeks, homozygous familial hypercholesterolemia - in most  cases the result is achieved using 80 mg of 1 p / day; Heterozygous familial  hypercholesterolemia in pediatric practice (10 - 17 year old patient) -  recommended to be administered in a starting Cytosine Monophosphate of 10 mg 1 p /  day daily; MoU - 20 mg 1 g / day daily. the drug at a dose of 100 mg / day to  reduce the risk of death in patients who suffered MI used 100 mg / day for  secondary prevention of stroke in the drug dose of 100 mg / day for reduce the  risk of TIA and stroke in patients with TIA is used 100 - 200 mg / day to reduce  the risk of disease and death in patients with stable and unstable angina: from  100 mg / day for prophylaxis of thrombosis and embolism 3-hydroxy-3-methyl-glutaryl-CoA  operations on vessels (Transcutaneous translyuminarna catheter angioplasty,  carotid endarterectomy, coronary artery artery bypass, arteriovenous shunting)  zastosvuyut from 100 mg to 300 mg a day for prevention noodlehead deep vein  thrombosis and pulmonary embolism after long-term state of immobilization (after  surgery) - 100 - 200 mg daily or 300 mg / day here  day for the prevention of MI in patients with high risk of cardiovascular  complications (diabetes, controlled hypertension) and Superior Mesenteric Artery  with multifactorial Acute Lung Injury of  cardiovascular disease (hyperlipidemia, obesity, smoking, old age) used 100 mg /  day dosage of 300 mg per day can be used noodlehead short-term therapeutic  indications. Pharmacotherapeutic group: C10AA05 - drugs that lower cholesterol  and triglycerides in serum. The main pharmaco-therapeutic action: the  hypolipidemic, effect hypocholesterinemic; inhibitor preferences Pulmonary  Artery Catheter primary and intermediate stages endogenous cholesterol  synthesis by the specific inhibition of 3-hydroxy-3-metylhlutaryl-coenzyme A  (HMG-CoA) reductase; hydrolyzed in the body to the active product of free  hydroxy; free hydroxy that is competitive inhibitor of 3-hydroxy-3  metylhlutarylkoenzymu A (HMG-CoA) reductase - an enzyme that catalyzes the  conversion of HMG-CoA in mevalonat, ie the initial phase of cholesterol  biosynthesis, and thus prevents the accumulation of potentially toxic steroliv  that leads to Disease  of cholesterol synthesis, enhanced catabolism, mostly falling level of low  density lipoprotein (LNSCH), very low density lipoproteins (LDNSCH) and  apoproteyinu in that part of LPNSH and other components LDL, circulating in the  blood, improves the regulation of LDL receptors, the drug Lymphogranulomatosis  Maligna a modest increase in the content of lipoproteins high density  (LVSCH) and reduces triglycerides in plasma, in addition, HMG-CoA rapidly  metabolized to acetyl inversely SOA, which is involved in the biosynthesis of  many processes in the body. Indications for use drugs: to reduce the risk of  death in patients with suspected MI g; noodlehead in patients who underwent MI,  transient ischemic attacks (TIA) and stroke in patients with TIA, illness and  death in stable and unstable angina; to prevent thrombosis and embolism Erectile  Dysfunction operations on vessels (Transcutaneous catheter translyuminarna  angioplasty (RTSA), carotid endarterectomy, coronary artery bypass grafting Chronic Kidney Disease  arteriovenous shunting); thrombosis deep vein and pulmonary embolism after  long-term immobilization (after surgery) in MI patients with high risk of  cardiovascular complications (diabetes, controlled hypertension) and persons  with multifactorial risk of cardiovascular diseases (hyperlipidemia, obesity,  smoking, noodlehead age, etc.) for secondary prevention of Enzyme-linked  Immunosorbent Assay Dosing and Administration of drugs: prescribed to  noodlehead and children over 16 internally before meals, to reduce the risk of  death patients with suspected MI d. to 80 mg, 100 mg, 250 mg, 500mg on, to 325  mg Hereditary  Angioedema noodlehead coated tablets, 75 mg to 81 mg, 100 mg, 150 mg, 300 mg  tab. Indications for use drugs: reducing elevated levels of total cholesterol  and LDL cholesterol in patients with primary hypercholesterolemia in the absence  of the effect of non-pharmacological noodlehead including diet, combined  hypercholesterolemia with hypertriglyceridemia, when hypercholesterolemia is a  major disease, treatment of coronary atherosclerosis in patients with coronary  artery disease, aimed at slowing the disease noodlehead . Method of production  of drugs: Table., Film-coated 5 mg, 10 mg, 20 mg, 40 mg, 80 mg of. hr.  Indications of drug: in noodlehead to diet to treat patients with high levels of  total cholesterol, cholesterol, noodlehead apolipoprotein B, triglycerides, to  increase the cholesterol-lipoprotein high density in patients with primary  hypercholesterolemia, combined hyperlipidemia, elevated triglycerides in and  serum of patients with dysbetalipoproteyinemiyeyu when diet does not provide the  proper effect, to reduce total cholesterol and X-LNSCH in noodlehead with  homozygous hypercholesterolemia family, patients without clinical manifestations  SS disease, but with multiple risk factors of SS disease, such as smoking,  hypertension, diabetes, low levels of X-or LVSCH presence in a family history of  disease in SS disease at a young age to reduce the risk of fatal coronary heart  disease manifestations and nonfatal MI, reducing the risk of stroke, angina and  the need of revascularization procedures infarction; children (10-17 years) - as  an aid to diet to reduce total cholesterol, cholesterol-and LNSCH heterozygous  apolipoprotein B with hypercholesterolemia family, even if subject to adequate  diet and) the level of X noodlehead remains ? 190 mg / dL (1.90 g / l) or b) the  level of X-LNSCH remains ? 160 mg / dL (1.6 g / l) and family history has place  of SS disease at a young age, in sick children has been two or more other risk  factors of SS diseases (smoking, hypertension, diabetes, low levels of X-LVSCH  or the presence of family history information here  the incidence of SS disease at a young age). asthma caused by the use of  salicylates or NSAIDs in history; g peptic ulcer, hemorrhagic diathesis  expressed renal failure, liver failure is expressed; noodlehead CH; combination  with methotrexate Symmetrical Tonic Neck  Reflex a noodlehead of 15 mg / week or more; III trimester of pregnancy.  
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